Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Palldtm1Zgwg
Name:	palladin, cytoskeletal associated protein; targeted mutation 1, Zhugang Wang
MGI ID:	MGI:3623949
Gene:	Palld  Location: Chr8:61964467-62355724 bp, - strand  Genetic Position: Chr8, 31.23 cM, cytoband B3.3
Alliance:	Palldtm1Zgwg page

Germline Transmission:	Earliest citation of germline transmission: J:100650
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting construct was designed to replace exons 17 and 18 and part of 19, sequence encoding the three Ig-like domains, with a PGK-neo cassette. Western blot failed to detect either the main isoform. (J:100650)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Palld Mutation:	61 strains or lines available

Original:	J:100650 Luo H, et al., Disruption of palladin results in neural tube closure defects in mice. Mol Cell Neurosci. 2005 Aug;29(4):507-15
All:	5 reference(s)