Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Abcc2tm1Ahs
Name:	ATP-binding cassette, sub-family member 2; targeted mutation 1, Alfred H Schinkel
MGI ID:	MGI:3621934
Synonyms:	Mrp2-, Mrp20
Gene:	Abcc2  Location: Chr19:43770747-43826771 bp, + strand  Genetic Position: Chr19, 36.67 cM
Alliance:	Abcc2tm1Ahs page

Germline Transmission:	Earliest citation of germline transmission: J:107822
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 1.7 kb fragment containing exons 4-6 was replaced with an inverted Pgk selection cassette. Complete absence of protein product was confirmed by Western blot analysis. (J:107822)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abcc2 Mutation:	90 strains or lines available

Original:	J:107822 Vlaming ML, et al., Carcinogen and anti-cancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice. J Pharmacol Exp Ther. 2006 Jul;318(1):319-27
All:	8 reference(s)