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Slc17a7tm1Edw
Targeted Allele Detail
Summary
Symbol: Slc17a7tm1Edw
Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7; targeted mutation 1, Robert H Edwards
MGI ID: MGI:3617803
Synonyms: VGLUT1-
Gene: Slc17a7  Location: Chr7:44813373-44825566 bp, + strand  Genetic Position: Chr7, 29.16 cM
Alliance: Slc17a7tm1Edw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105647
Parent Cell Line:  JM-1 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 and 3 and part of 4, encompassing the first two transmembrane domains, were removed via homologous recombination. (J:105647)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc17a7 Mutation:  39 strains or lines available
References
Original:  J:105647 Fremeau RT Jr, et al., Vesicular glutamate transporters 1 and 2 target to functionally distinct synaptic release sites. Science. 2004 Jun 18;304(5678):1815-9
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory