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Thy1tm1Rjmo
Targeted Allele Detail
Summary
Symbol: Thy1tm1Rjmo
Name: thymus cell antigen 1, theta; targeted mutation 1, R J Morris
MGI ID: MGI:3586862
Synonyms: Thy1-
Gene: Thy1  Location: Chr9:43954681-43959876 bp, + strand  Genetic Position: Chr9, 24.52 cM
Alliance: Thy1tm1Rjmo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:31610
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsThe insertion of a neomycin resistance cassette disrupted the codon for the third amino acid of the mature protein, located in the third exon. Immunoblotting and immunohistochemistry were both unable to detect protein in mutants. (J:31610)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Thy1 Mutation:  209 strains or lines available
References
Original:  J:31610 Nosten-Bertrand M, et al., Normal spatial learning despite regional inhibition of LTP in mice lacking Thy-1. Nature. 1996 Feb 29;379(6568):826-9
All:  24 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory