Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hipk1tm1Mak
Name:	homeodomain interacting protein kinase 1; targeted mutation 1, Tak Wah Mak
MGI ID:	MGI:3584135
Synonyms:	HIPK1-
Gene:	Hipk1  Location: Chr3:103647131-103698879 bp, - strand  Genetic Position: Chr3, 45.52 cM, cytoband F3
Alliance:	Hipk1tm1Mak page

Germline Transmission:	Earliest citation of germline transmission: J:99823
Parent Cell Line:	E14K (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to replace 2.7 kb of genomic DNA containing exon 1, encoding the putative kinase domain, with a neomycin resistance gene. Northern blot of mutant MEFs confirmed successful targeting. (J:99823)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hipk1 Mutation:	61 strains or lines available

Original:	J:99823 Kondo S, et al., Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1). Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5431-6
All:	3 reference(s)