Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Klf7tm1Rmz
Name:	Kruppel-like transcription factor 7 (ubiquitous); targeted mutation 1, Francesco Ramirez
MGI ID:	MGI:3581890
Synonyms:	DeltaK7-neo, Klf7-
Gene:	Klf7  Location: Chr1:64068606-64161441 bp, - strand  Genetic Position: Chr1, 32.31 cM, cytoband C1-C3
Alliance:	Klf7tm1Rmz page

Germline Transmission:	Earliest citation of germline transmission: J:99181
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed PGK-neo cassette replaced part of the 5'UTR and all of exon 1 by homologous recombination. In situ hybridization of mutant E13.5 spinal cord and P1 brain confirmed absence of transcript. Northern blot, RT-PCR and 5' RACE analyses further confirmed absence of transcript. (J:99181)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	10 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Klf7 Mutation:	21 strains or lines available

Original:	J:99181 Laub F, et al., Transcription Factor KLF7 Is Important for Neuronal Morphogenesis in Selected Regions of the Nervous System. Mol Cell Biol. 2005 Jul;25(13):5699-711
All:	8 reference(s)