Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tssk6tm1Grj
Name:	testis-specific serine kinase 6; targeted mutation 1, Gibbes R Johnson
MGI ID:	MGI:3580646
Synonyms:	SSTK-
Gene:	Tssk6  Location: Chr8:70354834-70356168 bp, + strand  Genetic Position: Chr8, 34.05 cM, cytoband C1
Alliance:	Tssk6tm1Grj page

Germline Transmission:	Earliest citation of germline transmission: J:98891
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding sequence was replaced with a floxed neo selection cassette. RT-PCR failed to detect transcript in testicular samples from mutant mice. Immunohistochemistry and in situ hybridization analyses also confirmed absence of expression. (J:98891)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tssk6 Mutation:	5 strains or lines available

Original:	J:98891 Spiridonov NA, et al., Identification and characterization of SSTK, a serine/threonine protein kinase essential for male fertility. Mol Cell Biol. 2005 May;25(10):4250-61
All:	3 reference(s)