Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Ehmt1tm1Yshk
Name:	euchromatic histone methyltransferase 1; targeted mutation 1, Yoichi Shinkai
MGI ID:	MGI:3575505
Synonyms:	GLP-
Gene:	Ehmt1  Location: Chr2:24680781-24809658 bp, - strand  Genetic Position: Chr2, 16.73 cM
Alliance:	Ehmt1tm1Yshk page

Germline Transmission:	Earliest citation of germline transmission: J:97244
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to replace exon 5 and part of exon 6 with a neomycin resistance gene. The deleted sequence encodes the catalytic core region of the SET domain. (J:97244)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ehmt1 Mutation:	90 strains or lines available

Original:	J:97244 Tachibana M, et al., Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9. Genes Dev. 2005 Apr 1;19(7):815-26
All:	11 reference(s)