Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Grm8tm1En
Name:	glutamate receptor, metabotropic 8; targeted mutation 1, Eric S Nisenbaum
MGI ID:	MGI:3574927
Synonyms:	mGlu8-
Gene:	Grm8  Location: Chr6:27275120-28135094 bp, - strand  Genetic Position: Chr6, 11.97 cM, cytoband A3
Alliance:	Grm8tm1En page

Germline Transmission:	Earliest citation of germline transmission: J:97019
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A neo replaced the sequence encoding amino acids 24-101. (J:97019)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Grm8 Mutation:	68 strains or lines available

Original:	J:97019 Zhai J, et al., Modulation of lateral perforant path excitatory responses by metabotropic glutamate 8 (mGlu8) receptors. Neuropharmacology. 2002 Aug;43(2):223-30
All:	6 reference(s)