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Adcyap1tm1Clw
Targeted Allele Detail
Summary
Symbol: Adcyap1tm1Clw
Name: adenylate cyclase activating polypeptide 1; targeted mutation 1, Christopher S Colwell
MGI ID: MGI:3521845
Synonyms: PACAP-
Gene: Adcyap1  Location: Chr17:93506448-93513967 bp, + strand  Genetic Position: Chr17, 60.67 cM
Alliance: Adcyap1tm1Clw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94880
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 3, 4 and part of 5 were replaced with a neomycin resistance cassette. RIA analysis confirmed the absence of protein product. (J:94880)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Tumor Data
List all tumor models in MMHCdb carrying Adcyap1tm1Clw
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adcyap1 Mutation:  22 strains or lines available
References
Original:  J:94880 Colwell CS, et al., Selective deficits in the circadian light response in mice lacking PACAP. Am J Physiol Regul Integr Comp Physiol. 2004 Nov;287(5):R1194-201
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory