Summary | Mutation origin | Mutation description | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol:	Gp1bbtm1Ware
Name:	glycoprotein Ib, beta polypeptide; targeted mutation 1, Jerry Ware
MGI ID:	MGI:3510459
Synonyms:	GP IbbetaNull
Gene:	Gp1bb  Location: Chr16:18439069-18441153 bp, - strand  Genetic Position: Chr16, 11.53 cM
Alliance:	Gp1bbtm1Ware page

Germline Transmission:	Earliest citation of germline transmission: J:93756
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A targeting vector was designed to replace codons in exon 2 with a neomycin resistance gene. (J:93756)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gp1bb Mutation:	2 strains or lines available

Original:	J:93756 Kato K, et al., Genetic deletion of mouse platelet glycoprotein Ibbeta produces a Bernard-Soulier phenotype with increased alpha-granule size. Blood. 2004 Oct 15;104(8):2339-44
All:	1 reference(s)