Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Fhittm1Tko
Name:	fragile histidine triad gene; targeted mutation 1, MM Taketo
MGI ID:	MGI:3057316
Synonyms:	Fhit-
Gene:	Fhit  Location: Chr14:11307738-12919681 bp, + strand  Genetic Position: Chr14, 5.61 cM, cytoband A2
Alliance:	Fhittm1Tko page

Germline Transmission:	Earliest citation of germline transmission: J:93269
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A PGK-neo replaced exon 5. (J:93269)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

List all tumor models in MMHCdb carrying Fhittm1Tko

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fhit Mutation:	22 strains or lines available

Original:	J:93269 Fujishita T, et al., Development of spontaneous tumours and intestinal lesions in Fhit gene knockout mice. Br J Cancer. 2004 Nov 18;91(8):1571-4
All:	1 reference(s)