Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol:	Pla2g6tm1Turk
Name:	phospholipase A2, group VI; targeted mutation 1, John Turk
MGI ID:	MGI:3055154
Synonyms:	IPLA2beta-
Gene:	Pla2g6  Location: Chr15:79170428-79212590 bp, - strand  Genetic Position: Chr15, 37.7 cM
Alliance:	Pla2g6tm1Turk page

Germline Transmission:	Earliest citation of germline transmission: J:92835
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance gene replaced exon 9. Northern blot and Western blot demonstrated lack of transcript and protein in mutant tissues. (J:92835)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pla2g6 Mutation:	65 strains or lines available

Original:	J:92835 Bao S, et al., Male mice that do not express group VIA phospholipase A2 produce spermatozoa with impaired motility and have greatly reduced fertility. J Biol Chem. 2004 Sep 10;279(37):38194-200
All:	34 reference(s)