Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ncoa6tm1Hhs
Name:	nuclear receptor coactivator 6; targeted mutation 1, Herbert H Samuels
MGI ID:	MGI:3046462
Synonyms:	NRC-
Gene:	Ncoa6  Location: Chr2:155232585-155315741 bp, - strand  Genetic Position: Chr2, 77.26 cM, cytoband H2
Alliance:	Ncoa6tm1Hhs page

Germline Transmission:	Earliest citation of germline transmission: J:91083
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The sequences encoding the LxxLL-1 region was replaced with a neo cassette via homologous recombination. (J:91083)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ncoa6 Mutation:	100 strains or lines available

Original:	J:91083 Mahajan MA, et al., The nuclear hormone receptor coactivator NRC is a pleiotropic modulator affecting growth, development, apoptosis, reproduction, and wound repair. Mol Cell Biol. 2004 Jun;24(11):4994-5004
All:	2 reference(s)