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Slc37a4tm1Jyc
Targeted Allele Detail
Summary
Symbol: Slc37a4tm1Jyc
Name: solute carrier family 37 (glucose-6-phosphate transporter), member 4; targeted mutation 1, Janice Yang Chou
MGI ID: MGI:3046091
Synonyms: G6PT-/-, Glc-6-PT
Gene: Slc37a4  Location: Chr9:44308243-44314263 bp, + strand  Genetic Position: Chr9, 24.84 cM, cytoband B
Alliance: Slc37a4tm1Jyc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86005
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe coding region of exon 1 as well as a portion of intron 1 were replaced with a neo cassette inserted by homologous recombination. Protein was undetected in homozygous mutant mice by Western blot analysis of liver and kidney microsomal preparations. (J:86005)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 10 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc37a4 Mutation:  17 strains or lines available
References
Original:  J:86005 Chen LY, et al., Impaired glucose homeostasis, neutrophil trafficking and function in mice lacking the glucose-6-phosphate transporter. Hum Mol Genet. 2003 Oct 1;12(19):2547-58
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory