Rps6ka3tm1Kry
Targeted Allele Detail
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| Symbol: |
Rps6ka3tm1Kry |
| Name: |
ribosomal protein S6 kinase polypeptide 3; targeted mutation 1, Gerard Karsenty |
| MGI ID: |
MGI:3042584 |
| Gene: |
Rps6ka3 Location: ChrX:158038652-158151240 bp, + strand Genetic Position: ChrX, 73.27 cM
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| Alliance: |
Rps6ka3tm1Kry page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:89403
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129X1/SvJ
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Insertion
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Mutation details: A floxed neo cassette, as well as three stop codons in three different frames, was inserted into exon 2. Western blot indicated absence of normal protein in mutant cells.
(J:89403)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Rps6ka3 Mutation: |
13 strains or lines available
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| Original: |
J:89403 Yang X, et al., ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell. 2004 Apr 30;117(3):387-98 |
| All: |
1 reference(s) |
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Analysis Tools
