Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ahnaktm1Vtm
Name:	AHNAK nucleoprotein; targeted mutation 1, Vincent T Marchesi
MGI ID:	MGI:3040870
Synonyms:	Ahnak-, Ahnak1-
Gene:	Ahnak  Location: Chr19:8966648-9054278 bp, + strand  Genetic Position: Chr19, 6.04 cM, cytoband A
Alliance:	Ahnaktm1Vtm page

Germline Transmission:	Earliest citation of germline transmission: J:89231
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed neo cassette replaced 5.3 kb of sequence encompassing the putative promoter, 5' UTR, and a segment of the coding region. Northern blot of mutant heart ventricles indicated no transcript was present, and absence of normal protein was confirmed by immunoblot. (J:89231)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ahnak Mutation:	316 strains or lines available

Original:	J:89231 Komuro A, et al., The AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells. Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4053-8
All:	3 reference(s)