Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Syn1tm1Noh
Name:	synapsin I; targeted mutation 1, Nobutaka Hirokawa
MGI ID:	MGI:3032534
Synonyms:	X-13
Gene:	Syn1  Location: ChrX:20726750-20787157 bp, - strand  Genetic Position: ChrX, 16.37 cM, cytoband A1-A4
Alliance:	Syn1tm1Noh page

Germline Transmission:	Earliest citation of germline transmission: J:30400
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin selection cassette replaced part of exon 1 and intron 1. Western blot analysis confirmed the absence of encoded protein in brain extracts derived from homozygous mice. (J:30400)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Syn1 Mutation:	22 strains or lines available

Original:	J:30400 Takei Y, et al., Synapsin I deficiency results in the structural change in the presynaptic terminals in the murine nervous system. J Cell Biol. 1995 Dec;131(6 Pt 2):1789-800
All:	2 reference(s)