Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Anxa2tm1Kah
Name:	annexin A2; targeted mutation 1, Katherine A Hajjar
MGI ID:	MGI:3028929
Synonyms:	A2-, Anxa2-
Gene:	Anxa2  Location: Chr9:69360978-69399074 bp, + strand  Genetic Position: Chr9, 38.58 cM
Alliance:	Anxa2tm1Kah page

Germline Transmission:	Earliest citation of germline transmission: J:87621
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 3 and 4 were replaced with a neomycin resistance gene inserted in antisense orientation. Reduced quantities of a smaller than normal sized mRNA were detectable in heart and lung extracts by Northern blot analysis. However, no immunodetectable protein could be identified by Western blot analysis. (J:87621)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Anxa2 Mutation:	46 strains or lines available

Original:	J:87621 Ling Q, et al., Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo. J Clin Invest. 2004 Jan;113(1):38-48
All:	21 reference(s)