Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Matn3tm1Asz
Name:	matrilin 3; targeted mutation 1, Attila Aszodi
MGI ID:	MGI:3028891
Synonyms:	Matn3-
Gene:	Matn3  Location: Chr12:8997929-9022028 bp, + strand  Genetic Position: Chr12, 3.96 cM
Alliance:	Matn3tm1Asz page

Germline Transmission:	Earliest citation of germline transmission: J:87676
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A PGK-neomycin cassette was inserted into exon 1 causing the partial deletion of the promoter region and the 5' part of exon 1 containing the ATG start site. Absence of protein product was demonstrated by immunohistochemistry on tissue sections at E13.5 as well as in situ hybridization to confirm the absence of mRNA transcripts. (J:87676)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Matn3 Mutation:	26 strains or lines available

Original:	J:87676 Ko Y, et al., Matrilin-3 is dispensable for mouse skeletal growth and development. Mol Cell Biol. 2004 Feb;24(4):1691-9
All:	5 reference(s)