Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	St14tm2Bug
Name:	suppression of tumorigenicity 14 (colon carcinoma); targeted mutation 2, Thomas H Bugge
MGI ID:	MGI:2683723
Gene:	St14  Location: Chr9:31000698-31043149 bp, - strand  Genetic Position: Chr9, 16.61 cM
Alliance:	St14tm2Bug page

Germline Transmission:	Earliest citation of germline transmission: J:86715
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Exon 2 was replaced with a neomycin selection cassette. (J:86715)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

16 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any St14 Mutation:	44 strains or lines available

Original:	J:86715 List K, et al., Loss of proteolytically processed filaggrin caused by epidermal deletion of Matriptase/MT-SP1. J Cell Biol. 2003 Nov 24;163(4):901-10
All:	4 reference(s)