Trpv4tm1Rck
Targeted Allele Detail
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Symbol: |
Trpv4tm1Rck |
Name: |
transient receptor potential cation channel, subfamily V, member 4; targeted mutation 1, J M Friedman |
MGI ID: |
MGI:2682656 |
Synonyms: |
trpv4- |
Gene: |
Trpv4 Location: Chr5:114760213-114796482 bp, - strand Genetic Position: Chr5, 55.99 cM, cytoband F
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Alliance: |
Trpv4tm1Rck page
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Trpv4tm1Rck/Trpv4tm1Rck mice show protection from UVB-induced skin injury
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:86560
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A single loxP site was left in place of exon 12 after cre mediated recombination of a single loxP site in intron 11 and a floxed neo cassette in intron 12. Protein was undetected by Western blot analysis of homozygous mutant kidney extracts.
(J:86560)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Trpv4 Mutation: |
57 strains or lines available
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Original: |
J:86560 Liedtke W, et al., Abnormal osmotic regulation in trpv4-/- mice. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13698-703 |
All: |
92 reference(s) |
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