Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Fabp3tm1Bin
Name:	fatty acid binding protein 3, muscle and heart; targeted mutation 1, Bert Binas
MGI ID:	MGI:2677970
Synonyms:	H-FABP-
Gene:	Fabp3  Location: Chr4:130202531-130209256 bp, + strand  Genetic Position: Chr4, 63.43 cM
Alliance:	Fabp3tm1Bin page

Germline Transmission:	Earliest citation of germline transmission: J:54614
Parent Cell Line:	HM-1 (ES Cell)
Strain of Origin:	129P2/OlaHsd-Hprt1b-m3

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A sequence fragment containing the entire coding region was replaced with an PGK-HRPT mini gene inserted by homologous recombination. Neither transcript nor protein was detected through Northern and Western blot analysis of homozygous mutant mice. (J:54614)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fabp3 Mutation:	67 strains or lines available

Original:	J:54614 Binas B, et al., Requirement for the heart-type fatty acid binding protein in cardiac fatty acid utilization. FASEB J. 1999 May;13(8):805-12
All:	19 reference(s)