About   Help   FAQ
Ubash3btm1Jni
Targeted Allele Detail
Summary
Symbol: Ubash3btm1Jni
Name: ubiquitin associated and SH3 domain containing, B; targeted mutation 1, James N Ihle
MGI ID: MGI:2670555
Synonyms: Elf1tm1Jni, p70 deficient, Sts1-, TULA-2-
Gene: Ubash3b  Location: Chr9:40922056-41069358 bp, - strand  Genetic Position: Chr9, 21.84 cM
Alliance: Ubash3btm1Jni page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79606
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 and 3 were replaced with a neomycin resistance gene in the antisensense orientation. Northern blot analysis indicated a lack of transcript while the absence of protein was confirmed immunologically. (J:79606)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ubash3b Mutation:  38 strains or lines available
References
Original:  J:79606 Carpino N, et al., Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein. Mol Cell Biol. 2002 Nov;22(21):7491-500
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory