Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Mbl1tm1Mnz
Name:	mannose-binding lectin (protein A) 1; targeted mutation 1, Michel C Nussenzweig
MGI ID:	MGI:2670116
Gene:	Mbl1  Location: Chr14:40873415-40881558 bp, + strand  Genetic Position: Chr14, 22.36 cM
Alliance:	Mbl1tm1Mnz page

Germline Transmission:	Earliest citation of germline transmission: J:84540
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Sequence encompassing all of exons 2 and 3 and a portion of exon 4 was replaced with a floxed neomycin selection cassette inserted by homologous recombination. (J:84540)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mbl1 Mutation:	23 strains or lines available

Original:	J:84540 Lee SJ, et al., Disseminated candidiasis and hepatic malarial infection in mannose-binding-lectin-A-deficient mice. Mol Cell Biol. 2002 Dec;22(23):8199-203
All:	1 reference(s)