Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Prdx2tm1Yu
Name:	peroxiredoxin 2; targeted mutation 1, Dae-Yeul Yu
MGI ID:	MGI:2668456
Synonyms:	Prdx2-, Prx II-
Gene:	Prdx2  Location: Chr8:85696251-85701440 bp, + strand  Genetic Position: Chr8, 41.4 cM
Alliance:	Prdx2tm1Yu page

Germline Transmission:	Earliest citation of germline transmission: J:84271
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Sequence encompassing exons 1 through 5 was replaced with a neomycin selection cassette inserted by homologous recombination. Western blot analysis of RBCs indicated an absence of protein in homozygous mutant mice. (J:84271)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prdx2 Mutation:	20 strains or lines available

Original:	J:84271 Lee TH, et al., Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice. Blood. 2003 Jun 15;101(12):5033-8
All:	39 reference(s)