Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fpr1tm1Gao
Name:	formyl peptide receptor 1; targeted mutation 1, Ji-Liang Gao
MGI ID:	MGI:2663726
Synonyms:	FPR-, KO-FPR, mfpr1-
Gene:	Fpr1  Location: Chr17:18096733-18104201 bp, - strand  Genetic Position: Chr17, 10.63 cM
Alliance:	Fpr1tm1Gao page

Germline Transmission:	Earliest citation of germline transmission: J:53354
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 150 bp fragment, encoding the extracellular loop of the fourth transmembrane domain, was replaced with a neomycin selection cassette inserted by homologous recombination. Only truncated transcript was detected in homozygous mutant mice by RT-PCR analysis. (J:53354)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Fpr1 Mutation:	28 strains or lines available

Original:	J:53354 Gao JL, et al., Impaired antibacterial host defense in mice lacking the N-formylpeptide receptor. J Exp Med. 1999 Feb 15;189(4):657-62
All:	33 reference(s)