Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hoxb13tm4Mrc
Name:	homeobox B13; targeted mutation 4, Mario R Capecchi
MGI ID:	MGI:2656729
Synonyms:	Hoxb13neo
Gene:	Hoxb13  Location: Chr11:96085142-96087436 bp, + strand  Genetic Position: Chr11, 59.63 cM
Alliance:	Hoxb13tm4Mrc page

Germline Transmission:	Earliest citation of germline transmission: J:82849
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: Exon 2 was disrupted by the insertion of a floxed neomycin selection cassette at codon 33. Hoxb13tm2Mrc was generated from this allele by in vivo cre mediated recombination. (J:82849)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxb13 Mutation:	9 strains or lines available

Original:	J:82849 Economides KD, et al., Hoxb13 mutations cause overgrowth of caudal spinal cord and tail vertebrae. Dev Biol. 2003 Apr 15;256(2):317-30
All:	1 reference(s)