Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pdzk1tm1Oko
Name:	PDZ domain containing 1; targeted mutation 1, Oliver Kocher
MGI ID:	MGI:2450706
Synonyms:	Pdzk1-
Gene:	Pdzk1  Location: Chr3:96736772-96778242 bp, + strand  Genetic Position: Chr3, 42.0 cM
Alliance:	Pdzk1tm1Oko page

Germline Transmission:	Earliest citation of germline transmission: J:81814
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: The gene was disrupted by insertion of a neomycin resistance cassette via homologous recombination. Absence of gene expression homozygous mutant kidneys was confirmed by Western blot analysis. (J:81814)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pdzk1 Mutation:	25 strains or lines available

Original:	J:81814 Kocher O, et al., Targeted Disruption of the PDZK1 Gene by Homologous Recombination. Mol Cell Biol. 2003 Feb;23(4):1175-80
All:	16 reference(s)