Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Hhextm1Cwb
Name:	hematopoietically expressed homeobox; targeted mutation 1, Clifford W Bogue
MGI ID:	MGI:2449914
Synonyms:	Hex-
Gene:	Hhex  Location: Chr19:37423289-37429179 bp, + strand  Genetic Position: Chr19, 32.28 cM, cytoband D1
Alliance:	Hhextm1Cwb page

Germline Transmission:	Earliest citation of germline transmission: J:81415
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The gene was disrupted by replacement of exons 1 and 2 with a PGK-neo cassette via homologous recombination. (J:81415)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	44 assay results
In Structures Affected by this Mutation:	17 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hhex Mutation:	16 strains or lines available

Original:	J:81415 Bogue CW, et al., Impaired B cell development and function in mice with a targeted disruption of the homeobox gene Hex. Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):556-61
All:	11 reference(s)