Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Eportm1Jni
Name:	erythropoietin receptor; targeted mutation 1, James N Ihle
MGI ID:	MGI:2388345
Synonyms:	EporH, Epor-H, H
Gene:	Epor  Location: Chr9:21870193-21874802 bp, - strand  Genetic Position: Chr9, 7.93 cM
Alliance:	Eportm1Jni page

Germline Transmission:	Earliest citation of germline transmission: J:70036
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The gene was truncated by replacement of exon 8 sequences encoding the distal half of the cytoplasmic domain with a neomycin resistance cassette. Expression of the mutant allele was confirmed by RT-PCR analysis of bone marrow RNA from homozygous mutant animals. (J:70036)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Epor Mutation:	25 strains or lines available

Original:	J:70036 Zang H, et al., The distal region and receptor tyrosines of the Epo receptor are non-essential for in vivo erythropoiesis. EMBO J. 2001 Jun 15;20(12):3156-66
All:	11 reference(s)