Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rasgrf1tm1Pds
Name:	RAS protein-specific guanine nucleotide-releasing factor 1; targeted mutation 1, Paul D Soloway
MGI ID:	MGI:2388130
Gene:	Rasgrf1  Location: Chr9:89791961-89909030 bp, + strand  Genetic Position: Chr9, 47.31 cM
Alliance:	Rasgrf1tm1Pds page

Germline Transmission:	Earliest citation of germline transmission: J:75397
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: A neomycin resistance cassette replaced sequence consisting of the 40 41-mer repeats that follow the differentially methylated domain. The selection cassette was removed by in vivo cre mediated recombination. (J:75397, J:185711)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rasgrf1 Mutation:	65 strains or lines available

Original:	J:75397 Yoon BJ, et al., Regulation of DNA methylation of Rasgrf1. Nat Genet. 2002 Jan;30(1):92-6
All:	3 reference(s)