Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cd55tm1Song
Name:	CD55 molecule, decay accelerating factor for complement; targeted mutation 1, Wen-Chao Song
MGI ID:	MGI:2387405
Synonyms:	Daf-, Daf1-
Gene:	Cd55  Location: Chr1:130366764-130390481 bp, - strand  Genetic Position: Chr1, 56.89 cM
Alliance:	Cd55tm1Song page

Germline Transmission:	Earliest citation of germline transmission: J:52968
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: Exons 1, 2 and 3, encoding the first and second short consensus repeats, were replaced with a neomycin selection cassette. Transcript was undetected in homozygous mutant mice by Northern blot analysis. (J:52968)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cd55 Mutation:	39 strains or lines available

Original:	J:52968 Sun X, et al., Role of decay-accelerating factor in regulating complement activation on the erythrocyte surface as revealed by gene targeting. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):628-33
All:	29 reference(s)