Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Ptprz1tm1Schl
Name:	protein tyrosine phosphatase receptor type Z, polypeptide 1; targeted mutation 1, Joseph Schlessinger
MGI ID:	MGI:2386268
Synonyms:	RPTPBeta-, RPTPbeta/zeta-
Gene:	Ptprz1  Location: Chr6:22875501-23052915 bp, + strand  Genetic Position: Chr6, 9.92 cM
Alliance:	Ptprz1tm1Schl page

Germline Transmission:	Earliest citation of germline transmission: J:64776
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin selection cassette inserted in the opposite orientation replaced exon 2 and precluded the translation of the carbonic anhydrase (CAH) domain. Transcript was undetected in homozygous mutant mice by Northern blot analysis of total brain RNA. (J:64776)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptprz1 Mutation:	139 strains or lines available

Original:	J:64776 Harroch S, et al., No obvious abnormality in mice deficient in receptor protein tyrosine phosphatase beta. Mol Cell Biol. 2000 Oct;20(20):7706-15
All:	14 reference(s)