Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pdlim3tm1Dsb
Name:	PDZ and LIM domain 3; targeted mutation 1, David S Bredt
MGI ID:	MGI:2385940
Gene:	Pdlim3  Location: Chr8:46338498-46372585 bp, + strand  Genetic Position: Chr8, 25.86 cM
Alliance:	Pdlim3tm1Dsb page

Germline Transmission:	Earliest citation of germline transmission: J:67358
Parent Cell Line:	JM-1 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 1, which encodes the first 30 amino acids of the protein product, was replaced with a neomycin selection cassette. The absence of transcript and protein in homozygous mutant mice was determined by Northern and Western blot analyses. (J:67358)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pdlim3 Mutation:	19 strains or lines available

Original:	J:67358 Jo K, et al., Actinin-associated LIM protein-deficient mice maintain normal development and structure of skeletal muscle. Mol Cell Biol. 2001 Mar;21(5):1682-7
All:	2 reference(s)