Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nfe2l1tm1Tow
Name:	nuclear factor, erythroid derived 2,-like 1; targeted mutation 1, Timothy Townes
MGI ID:	MGI:2385936
Synonyms:	Lcrf1tm1uab, Nfe2l1tm1Tmt
Gene:	Nfe2l1  Location: Chr11:96708240-96720794 bp, - strand  Genetic Position: Chr11, 60.12 cM, cytoband D-E
Alliance:	Nfe2l1tm1Tow page

Germline Transmission:	Earliest citation of germline transmission: J:39447
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: 3.5 kb of genomic sequence containing exons 3, 4, 5 and part of 6 was replaced with a neomycin selection cassette. RT-PCR analysis on 8 day old embryoid bodies derived from homozygous ES cells confirmed that no transcript is expressed from this allele. (J:39447)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	3 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfe2l1 Mutation:	39 strains or lines available

Original:	J:39447 Farmer SC, et al., The bZIP transcription factor LCR-F1 is essential for mesoderm formation in mouse development. Genes Dev. 1997 Mar 15;11(6):786-98
All:	4 reference(s)