Summary | Mutation origin | Mutation description | Find Mice (IMSR) | Notes | References

Symbol:	Rps6ka4tm1.2Gsc
Name:	ribosomal protein S6 kinase, polypeptide 4; targeted mutation 1.2, Gunther Schutz
MGI ID:	MGI:2384591
Gene:	Rps6ka4  Location: Chr19:6806578-6818004 bp, - strand  Genetic Position: Chr19, 5.08 cM
Alliance:	Rps6ka4tm1.2Gsc page

Germline Transmission:	Earliest citation of germline transmission: J:75113
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: A fragment containing 2 exons encoding the ATP-binding domain was excised, leaving a single loxP site. Truncated transcript was detected by RT-PCR analysis of total renal RNA isolated from heterozygous mice. This allele was generated by the breeding of mice carrying Rps6ka4tm1.1Gsc with transgenic mice expressing cre recombinase via a ubiquitous promoter. (J:75113)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rps6ka4 Mutation:	35 strains or lines available

Original:	J:75113 Casanova E, et al., Construction of a conditional allele of RSK-B/MSK2 in the mouse. Genesis. 2002 Feb;32(2):158-60
All:	1 reference(s)