Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Fgfr2tm2Lni
Name:	fibroblast growth factor receptor 2; targeted mutation 2, Peter Lonai
MGI ID:	MGI:2183526
Gene:	Fgfr2  Location: Chr7:129764181-129868538 bp, - strand  Genetic Position: Chr7, 73.19 cM
Alliance:	Fgfr2tm2Lni page

Germline Transmission:	Earliest citation of germline transmission: J:77698
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A stop codon was introduced into exon 8 and a floxed neomycin cassette was introduced into intron 9 via homologous recombination. Exon 8 is an Fgfr2IIIb-specific exon of the gene. (J:77698)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgfr2 Mutation:	87 strains or lines available

Original:	J:77698 Eswarakumar VP, et al., The IIIc alternative of Fgfr2 is a positive regulator of bone formation. Development. 2002 Aug 15;129(16):3783-93
All:	1 reference(s)