Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Fancgtm1Ada
Name:	Fanconi anemia, complementation group G; targeted mutation 1, Alan D'Andrea
MGI ID:	MGI:2183264
Synonyms:	Fancg-
Gene:	Fancg  Location: Chr4:43002343-43010506 bp, - strand  Genetic Position: Chr4, 22.97 cM, cytoband B1
Alliance:	Fancgtm1Ada page

Germline Transmission:	Earliest citation of germline transmission: J:72945
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 2-9 were replaced with an FRT-flanked neo cassette via homologous recombination. The targeting vector introduces stop codons in all 3 reading frames. Gene transcripts were absent in testes from homozygous mutant animals as assayed by RT-PCR analysis using primers to exons 5 and 6. (J:72945)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

5 anatomical structure(s)

List all tumor models in MMHCdb carrying Fancgtm1Ada

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fancg Mutation:	37 strains or lines available

Original:	J:72945 Yang Y, et al., Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9. Blood. 2001 Dec 1;98(12):3435-40
All:	9 reference(s)