Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rev3ltm1Ndew
Name:	REV3 like, DNA directed polymerase zeta catalytic subunit; targeted mutation 1, Niels De Wind
MGI ID:	MGI:2183197
Synonyms:	Rev3-
Gene:	Rev3l  Location: Chr10:39608114-39751207 bp, + strand  Genetic Position: Chr10, 21.04 cM
Alliance:	Rev3ltm1Ndew page

Germline Transmission:	Earliest citation of germline transmission: J:75450
Parent Cell Line:	IB10/E14IB10 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 10 kb region of the gene encoding DNA polymerase domains I, II, III, and IV, was replaced with a PGK-hygro cassette by homologous recombination. (J:75450)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rev3l Mutation:	118 strains or lines available

Original:	J:75450 Van Sloun PP, et al., Involvement of mouse Rev3 in tolerance of endogenous and exogenous DNA damage. Mol Cell Biol. 2002 Apr;22(7):2159-69
All:	2 reference(s)