Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Phlda1tm1Ywc
Name:	pleckstrin homology like domain, family A, member 1; targeted mutation 1, Yongwon Choi
MGI ID:	MGI:2182815
Synonyms:	TDAG51-
Gene:	Phlda1  Location: Chr10:111342147-111344506 bp, + strand  Genetic Position: Chr10, 58.7 cM
Alliance:	Phlda1tm1Ywc page

Germline Transmission:	Earliest citation of germline transmission: J:72947
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding region (exon 1) was replaced with a neomycin resistance gene via homologous recombination. Northern blot analysis of liver RNA from homozygous mutant animals confirmed the absence of gene expression. (J:72947)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Phlda1 Mutation:	9 strains or lines available

Original:	J:72947 Rho J, et al., TDAG51 Is Not Essential for Fas/CD95 Regulation and Apoptosis In Vivo. Mol Cell Biol. 2001 Dec;21(24):8365-70
All:	8 reference(s)