Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Mad2l1tm1Sorg
Name:	MAD2 mitotic arrest deficient-like 1; targeted mutation 1, Peter K Sorger
MGI ID:	MGI:2178781
Synonyms:	Mad2-
Gene:	Mad2l1  Location: Chr6:66512205-66518091 bp, + strand  Genetic Position: Chr6, 30.56 cM
Alliance:	Mad2l1tm1Sorg page

Germline Transmission:	Earliest citation of germline transmission: J:62829
Parent Cell Line:	D3 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A PGK-neomycin resistance cassette replaced the entire coding region. (J:62829)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

List all tumor models in MMHCdb carrying Mad2l1tm1Sorg

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mad2l1 Mutation:	14 strains or lines available

Original:	J:62829 Dobles M, et al., Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2. Cell. 2000 Jun 9;101(6):635-45
All:	14 reference(s)