Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	F3tm1Dco
Name:	coagulation factor III; targeted mutation 1, Desire Collen
MGI ID:	MGI:2178434
Synonyms:	mF3-, mTF-, TF -
Gene:	F3  Location: Chr3:121517186-121528697 bp, + strand  Genetic Position: Chr3, 52.94 cM
Alliance:	F3tm1Dco page

Germline Transmission:	Earliest citation of germline transmission: J:35120
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin selection cassette replaced the first exon of the gene. Northern blot analysis on embryonic fibroblasts derived from homozygous mice demonstrated that no detectable transcript was expressed from this allele. (J:35120)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any F3 Mutation:	24 strains or lines available

Original:	J:35120 Carmeliet P, et al., Role of tissue factor in embryonic blood vessel development. Nature. 1996 Sep 5;383(6595):73-5
All:	34 reference(s)