Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gsx1tm1Ssp
Name:	GS homeobox 1; targeted mutation 1, S Steven Potter
MGI ID:	MGI:2154448
Gene:	Gsx1  Location: Chr5:147125506-147127757 bp, + strand  Genetic Position: Chr5, 86.79 cM
Alliance:	Gsx1tm1Ssp page

Germline Transmission:	Earliest citation of germline transmission: J:31764
Parent Cell Line:	E14TG2a (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A PGK-HPRT resistance cassette replaced a large part of the first exon, the entire intron and the entire second exon including the sequences encoding the homeobox. (J:31764)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	25 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gsx1 Mutation:	11 strains or lines available

Original:	J:31764 Li H, et al., Gsh-1, an orphan Hox gene, is required for normal pituitary development. EMBO J. 1996 Feb 15;15(4):714-24
All:	13 reference(s)