Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gnao1tm1Lbi
Name:	guanine nucleotide binding protein, alpha O; targeted mutation 1, Lutz Birnbaumer
MGI ID:	MGI:2152685
Synonyms:	Gnao1.1tm1LBi, Go1alpha
Gene:	Gnao1  Location: Chr8:94536781-94696016 bp, + strand  Genetic Position: Chr8, 45.94 cM
Alliance:	Gnao1tm1Lbi page

Germline Transmission:	Earliest citation of germline transmission: J:46898
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: The neo cassette was inserted into exon 6. No protein was detected in homogenates from homozygous targeted mice by ADP-ribosylation with pertussis toxin. (J:46898)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gnao1 Mutation:	29 strains or lines available

Original:	J:46898 Jiang M, et al., Multiple neurological abnormalities in mice deficient in the G protein Go. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3269-74
All:	15 reference(s)