Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cenpbtm1Rpe
Name:	centromere protein B; targeted mutation 1, Roger A Pedersen
MGI ID:	MGI:1932104
Synonyms:	CENP-B null
Gene:	Cenpb  Location: Chr2:131019209-131021974 bp, - strand  Genetic Position: Chr2, 63.29 cM
Alliance:	Cenpbtm1Rpe page

Germline Transmission:	Earliest citation of germline transmission: J:50001
Parent Cell Line:	JM-1 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced 660 bp of coding sequence. Northern and Western blot analyses of lung fibroblasts did not detect Cenpb transcript or protein in homozygous mutant mice. (J:50001)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cenpb Mutation:	18 strains or lines available

Original:	J:50001 Perez-Castro AV, et al., Centromeric protein B null mice are viable with no apparent abnormalities. Dev Biol. 1998 Sep 15;201(2):135-43
All:	1 reference(s)