Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fgf4tm1Gol
Name:	fibroblast growth factor 4; targeted mutation 1, Mitchell Goldfarb
MGI ID:	MGI:1931072
Synonyms:	Fgf4-
Gene:	Fgf4  Location: Chr7:144415123-144418982 bp, + strand  Genetic Position: Chr7, 88.88 cM
Alliance:	Fgf4tm1Gol page

Germline Transmission:	Earliest citation of germline transmission: J:22275
Parent Cell Line:	CB1-4 (ES Cell)
Strain of Origin:	C57BL/6J x (Rb(11.16)2H x Rb(16.17)32Lub)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A promoterless neomycin gene was inserted into exon 1, and sequences corresponding to the first 109 amino acids were deleted. (J:22275)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	60 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgf4 Mutation:	29 strains or lines available

Original:	J:22275 Feldman B, et al., Requirement of FGF-4 for postimplantation mouse development. Science. 1995 Jan 13;267(5195):246-9
All:	7 reference(s)