Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gata2tm1Sho
Name:	GATA binding protein 2; targeted mutation 1, Stuart Orkin
MGI ID:	MGI:1857743
Synonyms:	GATA-2-
Gene:	Gata2  Location: Chr6:88170873-88184014 bp, + strand  Genetic Position: Chr6, 39.2 cM
Alliance:	Gata2tm1Sho page

Germline Transmission:	Earliest citation of germline transmission: J:20316
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced 1 kb of sequence containing exon 2. RT-PCR analysis did not detect transcripts in differentiating embryoid bodies derived from homozygous ES cell lines. (J:20316)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	56 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gata2 Mutation:	26 strains or lines available

Original:	J:20316 Tsai FY, et al., An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature. 1994 Sep 15;371(6494):221-6
All:	24 reference(s)