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Ntf5tm1Jae
Targeted Allele Detail
Summary
Symbol: Ntf5tm1Jae
Name: neurotrophin 5; targeted mutation 1, Rudolf Jaenisch
MGI ID: MGI:1857233
Synonyms: NT4, NT-4 -, Ntf4-
Gene: Ntf5  Location: Chr7:45063119-45066603 bp, + strand  Genetic Position: Chr7, 29.3 cM
Alliance: Ntf5tm1Jae page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:25566
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    The entire coding region of the gene was replaced by a PGK-neomycin cassette. (J:25566)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ntf5 Mutation:  12 strains or lines available
References
Original:  J:25566 Liu X, et al., Sensory but not motor neuron deficits in mice lacking NT4 and BDNF. Nature. 1995 May 18;375(6528):238-41
All:  36 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory