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Emx2 cDNA Probe Detail
Nucleotide
Probe/Clone
  • Name
    Emx2 cDNA
  • Sequence Type
    cDNA
  • ID
    MGI:9330
  • Region Covered
    partial coding sequence
  • Child Clone
  • Vector Type
    Plasmid
  • Insert Site
    AluI/EcoRI
  • Insert Size
    0.65kb
Source
  • Species
    mouse, laboratory
  • Age
    embryonic day 11.0
  • Tissue
    embryo
Genes
Emx2 empty spiracles homeobox 2
Expression
  • Assay Results
    185
References
J:1461 Simeone A, et al., Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex. EMBO J. 1992 Jul;11(7):2541-50
J:29276 Acampora D, et al., Forebrain and midbrain regions are deleted in Otx2-/- mutants due to a defective anterior neuroectoderm specification during gastrulation. Development. 1995 Oct;121(10):3279-90
J:30828 Ang SL, et al., A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain. Development. 1996 Jan;122(1):243-52
J:33995 Gulisano M, et al., Emx1 and Emx2 show different patterns of expression during proliferation and differentiation of the developing cerebral cortex in the mouse. Eur J Neurosci. 1996 May;8(5):1037-50
J:36832 Stoykova A, et al., Forebrain patterning defects in Small eye mutant mice. Development. 1996 Nov;122(11):3453-65
J:37631 Pellegrini M, et al., Dentate gyrus formation requires Emx2. Development. 1996 Dec;122(12):3893-8
J:41809 Filosa S, et al., goosecoid and HNF-3 beta genetically interact to regulate neural tube patterning during mouse embryogenesis. Development. 1997 JUL;124(14):2843-2854
J:48135 Fernandez AS, et al., Expression of the Emx-1 and Dlx-1 homeobox genes define three molecularly distinct domains in the telencephalon of mouse, chick, turtle and frog embryos: implications for the evolution of telencephalic subdivisions in amniotes. Development. 1998 Jun;125(11):2099-111
J:53903 Theil T, et al., Gli3 is required for Emx gene expression during dorsal telencephalon development. Development. 1999 Aug;126(16):3561-71
J:59472 Dou CL, et al., Dual role of brain factor-1 in regulating growth and patterning of the cerebral hemispheres. Cereb Cortex. 1999 Sep;9(6):543-50
J:59923 Tole S, et al., Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J). Dev Biol. 2000 Jan 15;217(2):254-65
J:72659 Tole S, et al., Emx2 is required for growth of the hippocampus but not for hippocampal field specification. J Neurosci. 2000 Apr 1;20(7):2618-25
J:82457 Ligon KL, et al., Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia. Development. 2003 May;130(10):2275-87
J:93057 Schuurmans C, et al., Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways. EMBO J. 2004 Jul 21;23(14):2892-902
J:117873 Chang YS, et al., Graded expression of Zfp462 in the embryonic mouse cerebral cortex. Gene Expr Patterns. 2007 Feb;7(4):405-12

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory